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TeachMeFinance.com - explain Reference dose (RfD) Reference dose (RfD) The term 'Reference dose (RfD)' as it applies to the area of hazardous materials can be defined as 'An EPA estimate, with uncertainty or safety factors built in, of the daily lifetime dose of a substance that is unlikely to cause harm in humans'. Previous 5 Terms: reedbuck reef reef breakwater Reentry interval REF Next 5 Terms: Reference man Reference Mark Reference month reference plane reference point About the author Mark McCracken Author: Mark McCracken is a corporate trainer and author living in Higashi Osaka, Japan. He is the author of thousands of online articles as well as the Business English textbook, "25 Business Skills in English". Copyright © 2005-2011 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Please read the disclaimer for details.